Göbel et al. In a recent study with 18,544 participants, headaches after Covid-19 vaccinations. Depending on the vaccine, the headache occurred at different times and with varying intensity. On average, headaches started 12 hours after vaccination and took about 23 hours. Headaches were found particularly quickly at Sputnik V (17 hours), while the MRNA vaccines Comirnaty (26 hours) and Spikevax (22 hours) later worked. Spikevax caused stronger headache tints, while Vaxzevria more often accompanied with complex accompanying symptoms.
The results help to distinguish headaches better from other, possibly dangerous causes such as thrombosis. On the basis of the data, new diagnostic criteria for post -vaccinal headaches can be developed.
Göbel, CH, Heinze, A., Heinze-Kuhn, K., Karstedt, S., Morscheck, M., Tashiro, L., Cirkel, A., Hamid, Q., Halwani, R., Temsah, M. -H., Ziemann, M., Görg, S., Münte, T., & Göbel, H. (2025). Comparison of Phenotypes of Headaches After Covid-19 Vaccinations Differential According to The Vaccine Used. Vaccines , 13 (2), 113. Https://doi.org/10.3390/vaccines13020113
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