Almotriptan – the all-rounder
Compared to the pioneering drug sumatriptan, almotriptan (Almogran) acts even more specifically on the blood vessels of the meninges. It specifically inhibits the inflammatory processes in the meninges during a migraine attack.
Furthermore, its absorption into the bloodstream after passing through the stomach is 70 percent higher than that of all other triptans. Therefore, when taken as a tablet, it is reliably absorbed in the stomach and can thus reliably release its active ingredients and reach the necessary site of action, even in cases of nausea and vomiting. Almotriptan also reduces the typical migraine symptoms of nausea, and sensitivity to light and sound.
This results in a particularly reliable effect.
Almotriptan is very well tolerated. Almotriptan causes fewer side effects, such as chest tightness or heart problems, than sumatriptan.
Almotriptan is offered in a 12.5 mg tablet.
Since May 1, 2011, it has also been available without a prescription as Dolortriptan.
Special features at a glance
- Within two hours of taking almotriptan, 64 percent of patients reported a reduction in pain and 37 percent reported complete freedom from pain.
- The effect begins after just 30 minutes.
- Furthermore, the effectiveness of almotriptan does not diminish over the long term.
- Recurrent headaches are also less frequent in patients taking almotriptan (18 to 27 percent) than in those taking riza and sumatriptan (30 to 40 percent).
- In clinical trials, almotriptan was found to be very well tolerated. Adverse events were no more frequent with 12.5 mg almotriptan than with placebo.
- Almotriptan thus combines many advantages of triptans, is fast, gentle and sustainably effective, which has earned almotriptan the nickname “all-rounder”.